The Center for Electron Paramagnetic Resonance (EPR) Imaging in Vivo Physiology at the University of Chicago, is a National Institutes of Biomedical Imaging and Bioengineering, NIH, supported Technology Development Resource. The aim of the Center is the development of new imaging technologies sensitive to the functioning of the normal and diseased tissues of living animals. The Center develops EPR instrumentation, spin probes and imaging methodologies. We use very low frequency EPR technology to maximize the depth in animal tissue to which the technique is sensitive. EPR imaging is used in the preclinical studies of tissue microenvironment, including oxygen partial pressure, pH and redox potential.
The Center is a consortium between the University of Chicago, the University of Denver, the University of Maryland and Novosibirsk Institute of Organic Chemistry (NIOC), Russia.