Yamuna Krishnan

Krishnan's lab elicits new functions from DNA beyond that of its traditional role as Nature’s genetic material. DNA nanodevices are nanoscale assemblies, formed from a collection of synthetic DNA strands, that can have artificial function engineered into them. Krishnan’s lab has created quantitative imaging technology that uses DNA nanodevices as fluorescent reporters to map second messengers in real time in cells and in living organisms. Her research uses these DNA nanodevices to understand how the chemistry of sub-cellular compartments called organelles regulate the functions of living cells in health and disease.